Opening Day 2010 takes place on Monday, April 5, with the Opening Night matchup between the Red Sox and Yankees set for the night before, April 4 at 8 p.m.

Opening Night

Yankees Red Sox on Opening Night, Sunday April 4

Opening Day Match-ups

Philadelphia Phillies at the Washington Nationals 1:05pm
Florida Marlins at the New York Mets 1:10pm
Saint Louis Cardinals at the Cincinnati Reds 1:10pm
Los Angeles Dodgers at the Pittsburgh Pirates 1:35pmBuy
Cleveland Indians at the Chicago White Sox 2:05pm
Toronto Blue Jays at the Texas Rangers 2:05pm
Colorado Rockies at the Milwaukee Brewers 2:10pm
Chicago Cubs at the Atlanta Braves 4:10pm
Detroit Tigers at the Kansas City Royals 4:10pm
San Diego Padres at the Arizona Diamondbacks 5:10pm
San Francisco Giants at the Houston Astros 7:05pm
Minnesota Twins at the Los Angeles Angels 10:05pm
Seattle Mariners at the Oakland Athletics 10:05pm

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